Non-invasive prenatal testing has altered positive predictive value following transfer of a euploid blastocyst
نویسندگان
چکیده
منابع مشابه
Improving the Positive Predictive Value of Non-Invasive Prenatal Screening (NIPS)
We evaluated performance characteristics of a laboratory-developed, non-invasive prenatal screening (NIPS) assay for fetal aneuploidies. This assay employs massively parallel shotgun sequencing with full automation. GC sequencing bias correction and statistical smoothing were performed to enhance discrimination of affected and unaffected pregnancies. Maternal plasma samples from pregnancies wit...
متن کاملNon-invasive prenatal testing.
BACKGROUND Non-invasive prenatal testing (NIPT), also known as cell-free DNA testing and non-invasive prenatal screening (NIPS), is an important addition to the range of screening tests for fetal chromosomal abnormalities. For trisomy 21 in particular, NIPT is superior to other screening modalities. However, NIPT has limitations and complexities that requesting clinicians and their patients sho...
متن کاملPositive Attitudes towards Non-Invasive Prenatal Testing (NIPT) in a Swedish Cohort of 1,003 Pregnant Women
OBJECTIVE The clinical utilization of non-invasive prenatal testing (NIPT) for identification of fetal aneuploidies is expanding worldwide. The aim of this study was to gain an increased understanding of pregnant women's awareness, attitudes, preferences for risk information and decision-making concerning prenatal examinations with emphasis on NIPT, before its introduction into Swedish healthca...
متن کاملThe value and role of non-invasive prenatal testing in a select South African population.
BACKGROUND Concerns have been raised about the injudicious use of non-invasive prenatal testing (NIPT) using cell-free DNA (cfDNA), which often leads to inaccuracies in interpretation of the role and value of cfDNA in prenatal screening. OBJECTIVES To determine the value and role of NIPT in a select South African (SA) population. METHODS A retrospective review of patients who elected to h...
متن کاملUveal Melanoma: Non-Invasive Predictive Testing
Uveal melanoma (UM) is the most common intraocular tumor in the western population. Overall survival has not improved during the past decades, despite a shift towards more conservative eye treatments. 1 Currently, the choice of treatment for UM depends on size and location of the tumor, secondary effects of the tumor on the eye (for instance inflammation or neovascular glaucoma), the status of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2019
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2019.07.180